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DeCS
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Descriptor English:
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Neoplasm Proteins
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Descriptor Spanish:
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Proteínas de Neoplasias
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Descriptor Portuguese:
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Proteínas de Neoplasias
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Synonyms English:
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Proteins, Neoplasm
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Tree Number:
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D12.776.624
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Definition English:
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Proteins whose abnormal expression (gain or loss) are associated with the development, growth, or progression of NEOPLASMS. Some neoplasm proteins are tumor antigens (ANTIGENS, NEOPLASM), i.e. they induce an immune reaction to their tumor. Many neoplasm proteins have been characterized and are used as tumor markers (BIOMARKERS, TUMOR) when they are detectable in cells and body fluids as monitors for the presence or growth of tumors. Abnormal expression of ONCOGENE PROTEINS is involved in neoplastic transformation, whereas the loss of expression of TUMOR SUPPRESSOR PROTEINS is involved with the loss of growth control and progression of the neoplasm. |
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Indexing Annotation English:
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IM & coord with specific protein (IM) + specific histol type (IM) + specific organ/neoplasms term (IM); Manual 24.4.4.4
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See Related English:
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Antigens, Neoplasm
Biomarkers, Tumor
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Allowable Qualifiers English:
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Record Number:
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9556
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Unique Identifier:
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D009363
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Occurrence in VHL:
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Similar:
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DeCS
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